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chloroquine will boost the level or result of codeine by influencing hepatic enzyme CYP2D6 metabolism. Use Caution/Keep an eye on. Helps prevent conversion of codeine to its Lively metabolite morphine.
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fentanyl iontophoretic transdermal procedure and codeine each boost sedation. Stay clear of or Use Alternate Drug. Limit use to clients for whom option procedure choices are inadequate
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This medication might interfere with selected professional medical/lab exams (for example amylase/lipase amounts, allergy skin examination, brain scan for Parkinson's ailment), probably producing false examination final results. Make certain lab staff and your Medical doctors know you utilize this drug.
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Lifetime-threatening respiratory despair and death have happened in small children who obtained codeine; codeine is subject matter to variability in metabolism centered upon CYP2D6 genotype; based upon publish-advertising and marketing reviews, little ones < 12 yrs look like more susceptible to respiratory depressant consequences of codeine, notably if there are threat things for respiratory melancholy; conditions of Demise are already noted during the put up-operative period pursuing tonsillectomy and/or adenoidectomy, and lots of of the children experienced evidence of remaining read more ultra-immediate metabolizers of codeine
This is simply not a complete list of feasible Unintended effects. Should you discover other outcomes not listed higher than, Get in touch with your medical doctor or pharmacist.